Diethyl Pyrocarbonate For Molecular Biology (DEPC, DEP, Diethyl dicarbonate) CAS No 1609-47-8 Purity 96.0% (71827)

Diethyl Pyrocarbonate

For Molecular Biology

• 🔬 DNA Structural Studies: DEPC is employed to investigate the architecture of double-stranded DNA by chemically modifying specific nucleophilic sites, allowing researchers to infer conformational or functional aspects based on reactivity.
• Protein Chemistry: It selectively modifies histidyl residues in proteins, making it a valuable reagent in studies focused on active site characterization, protein-protein interactions, or conformational analysis. The reaction typically involves carbethoxylation of imidazole side chains, influencing histidine’s role in enzymatic or binding functions. Store at 2 – 8°C

WARNING

Hazard statements: May cause respiratory irritation. Causes skin irritation. Causes serious eye irritation.

Precautionary statements

Prevention: Avoid breathing dust/fume/gas/mist/vapours/spray. Wash thoroughly after handling. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection.

Response: IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If eye irritation persists: Get medical advice/attention.

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